What is Chymopapain?
Chymopapain (trand name Chymodiactin) is a proteolytic agitator abandoned from the acrylic of papaya (Carica papaya). It is a medication acclimated to amusement herniated lower lumbar discs in the spine. Chymopapain injections are commonly accustomed beneath local, rather than general, anaesthesia. The dosage for a individual intervertebral disc is 2 to 4 nanokatals, with a best dosage per accommodating of 8 nanokatals.
The auction and administration of chymopapain was discontinued in the United States on January 27, 2003.
Serious side effects from the use of chymopapain include anaphylaxis, paralysis of the legs, or death.
Chymopapain is injected directly into a herniated ("slipped'') disk in the spine to dissolve part of the disk and relieve the pain and other problems caused by the disk pressing on a nerve. Before you receive chymopapain, you will be given an anesthetic (either a general anesthetic to put you to sleep or a local anesthetic).
Very rarely, use of chymopapain may cause serious side effects, including paralysis of the legs or death. Another dangerous side effect of chymopapain injection is a severe allergic reaction called anaphylaxis. This side effect occurs in less than 1% of the patients receiving the medicine, but it occurs more often in women than in men. Before receiving chymopapain, you should discuss its use, and the possibility of anaphylaxis or other serious side effects, with your doctor.
Chymopapain injections are given only in a hospital, usually in an operating room, by your surgeon.