What is Ghrelin?
Ghrelin is a 28 amino acerbic peptide that is the accustomed ligand for the advance hormone secretagogue receptor (GHS-R). Based on its structure, it is a affiliate of the motilin ancestors of peptides. When administered peripherally or into the axial afraid system, ghrelin stimulates beard of advance hormone, increases aliment intake, and produces weight gain.
Ghrelin, which is produced by the stomach, increases during periods of abnegation or beneath altitude associated with abrogating activity antithesis such as starvation or anorexia. In contrast, ghrelin levels are low afterwards bistro or with hyperglycemia, and in obesity. Accumulating affirmation indicates that ghrelin plays a axial role in the neurohormonal adjustment of aliment assimilation and activity homeostasis.